Daily energy, mental clarity, and healthy aging — in a refreshing, doctor-designed effervescent.*
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Inside the formula
The hero ingredients in VitalFactors — built to support cellular energy, recovery, and healthy aging in a single morning glass.*
Cellular energy
Nicotinamide Riboside Chloride (Super NAD+) — a clinically studied precursor that supports your cellular NAD⁺ levels.*
Natural HGH support
L-Arginine, Glycine, L-Glutamine and L-Ornithine — amino acids studied as natural HGH secretagogues.*
Antioxidant defense
Extramel® SOD — a patented melon-derived enzyme that supports your body’s defense against oxidative stress.*
Longevity polyphenol
resVida® — clinically studied red-grape polyphenol associated with healthy-aging pathways.*
The Approach
NAD+ is a coenzyme involved in cellular energy production and DNA repair. Research suggests NAD+ levels decline with age (Imai et al., Nature Reviews 2014).*
A balanced amino-acid profile and clinical-grade vitamin and mineral panel provide the cofactors involved in normal cellular metabolism, recovery, and healthy aging.*
Nicotinamide Riboside Chloride, Niacinamide, and CoQ10 are nutrients involved in NAD+biology and mitochondrial function.*
A clinically formulated blend of amino acids — L-Arginine, Glycine, L-Glutamine, and L-Ornithine — alongside antioxidants supports daily nutrition for healthy aging.*
How it works
VitalFactors is a daily formula that combines NAD+-related cofactors, antioxidants, amino acids, and a full vitamin and mineral panel into two effervescent tablets — built to give any healthy adult a complete nutritional foundation in a single glass of water.*
Drop two effervescent tablets in 8–12 oz of water in the morning. Stay on the 5-on / 2-off rhythm.
The effervescent format dissolves the actives in water before you drink — designed for efficient absorption.
A complete vitamin, mineral, amino-acid, and antioxidant blend — daily nutritional support for any healthy adult.*
Compare
| Feature | VitalFactors | Typical NAD⁺ supplement |
|---|---|---|
| NAD⁺ precursor | Nicotinamide Riboside Chloride (Super NAD+) | Often NMN or none |
| Amino-acid blend (Arginine, Glycine, Glutamine, Ornithine) | ||
| Antioxidant defense (Resveratrol, SOD, OPCs) | ||
| Foundational vitamin & mineral panel | ||
| Doctor-formulated since 1984 | ||
| Effervescent — absorbs in solution | ||
| Monthly cost (subscribe) | $89/mo | $60–$120/mo |
What you get
Nicotinamide Riboside Chloride and CoQ10 support NAD+ biology and mitochondrial function — the foundation of how your cells make energy.*
Aminopeptide blend with L-Arginine, Glycine, and L-Glutamine, alongside a full vitamin and mineral panel — daily nutritional support for focus and mental performance.*
Resveratrol, Extramel® SOD, EGCG, and N-Acetyl L-Cysteine — research-backed antioxidants that support recovery from daily oxidative stress.*
A clinically formulated stack supporting two pathways at once — cellular energy through NAD+ biology, plus antioxidant defense for skin, hair, and connective tissue.*
Recommended By
Fitness and nutrition unite for a vibrant, healthy lifestyle. That's why I take VitalFactors as my favorite natural energizer.
I take VitalFactors and give it to my patients. The only 'complaint' is that it makes our hair grow so fast, we need to visit the salon more.
VitalFactors is my fountain of youth — I have been taking it for over 20 years.
Customer Reviews
Popular topics
I have been taking VitalFactors and other MDR vitamins for over 20 years. When you think I topped the charts before Elvis and I am still active and strong at 90, you can see why I call VitalFactors my 'Fountain of Youth.'
I take VitalFactors and give it to my patients. The only 'complaint' is that it makes our hair grow so fast, we need to visit the salon more.
I was dragging thru the day and even felt like nodding off while driving. That was it. I tried Vital Factors because my friend said it gave her back her natural youthful energy. Within the first two days of me taking the drink, I was no longer getting tired. I felt more alert and had more focus to get more done. I also found I slept better. So grateful I found you. I will tell all my friends that aging doesn’t have to slow us down. Try MDR Vital Factors!
Been taking VitalFactors for two months. Love the taste so much that it has become my favorite drink. Hate that I’m supposed to skip 2 days a week but I follow the regimen and am feeling amazing.
I was getting tired and needing to nap in the afternoon. I was putting off projects because I did not have the energy to tackle them. Now just one month after taking Vital Factors, I am my old me again…or i should say the YOUNGER ME again. I have more energy, mental sharpness, and don’t get tired but I fall asleep better at night. I am back to bicycling and swimming and feel healthier. Thanks for making this formula.
FAQ
Individual results vary. Many customers report feeling a difference in energy and focus within the first few weeks of consistent use on the 5-on / 2-off rhythm. Because VitalFactors works through nutritional support rather than a stimulant effect, most benefits build gradually with regular use.*
Important information
Do not take this product if you have kidney, liver, or gastrointestinal disease, or cancer. Consult your physician first if you are on a sodium- or potassium-restricted diet.
VitalFactors contains soy isoflavones (sourced from soy). Free of gluten and artificial dyes. Not for individuals with a history of hypersensitivity to any ingredient — review the full Supplement Facts panel before use.
Not intended for individuals who are pregnant or nursing. Consult a health-care practitioner before using.
If you take prescription medications — particularly blood thinners, diabetes medications, or hormone therapies — consult your physician before starting VitalFactors.
Helpful tip: many customers paste their current medication list together with our Supplement Facts panel into ChatGPT to surface possible interactions worth discussing with their physician. It's not medical advice — just a useful starting point for that conversation.
Store in a cool, dry place away from direct sunlight or moisture. Do not store in the refrigerator. Keep out of reach of children or pets.
Contains no caffeine. Will not cause jitters or stimulant-type spikes.