Doctor-designed effervescent formulated to support daily energy, mental clarity, and healthy aging — for any healthy adult.*
Choose your plan
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
The Approach
NAD+ is a coenzyme involved in cellular energy production and DNA repair. Research suggests NAD+ levels decline with age (Imai et al., Nature Reviews 2014).*
A balanced amino-acid profile and clinical-grade vitamin and mineral panel provide the cofactors involved in normal cellular metabolism, recovery, and healthy aging.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Nicotinamide Riboside Chloride, Niacinamide, and CoQ10 are nutrients involved in NAD+biology and mitochondrial function.*
A clinically formulated blend of amino acids — L-Arginine, Glycine, L-Glutamine, and L-Ornithine — alongside antioxidants supports daily nutrition for healthy aging.*
How it works
VitalFactors is a daily formula that combines NAD+-related cofactors, antioxidants, amino acids, and a full vitamin and mineral panel into two effervescent tablets — built to give any healthy adult a complete nutritional foundation in a single glass of water.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Drop two effervescent tablets in 8–12 oz of water in the morning. Stay on the 5-on / 2-off rhythm.
The effervescent format dissolves the actives in water before you drink — designed for efficient absorption.
A complete vitamin, mineral, amino-acid, and antioxidant blend — daily nutritional support for any healthy adult.*
Compare
| Feature | VitalFactors | Typical NAD⁺ supplement |
|---|---|---|
| NAD⁺ precursor | Nicotinamide Riboside Chloride (Super NAD+) | Often NMN or none |
| Amino-acid blend (Arginine, Glycine, Glutamine, Ornithine) | ||
| Antioxidant defense (Resveratrol, SOD, OPCs) | ||
| Foundational vitamin & mineral panel | ||
| Doctor-formulated since 1984 | ||
| Effervescent — absorbs in solution | ||
| Monthly cost (subscribe) | $89/mo | $60–$120/mo |
What you get
Nicotinamide Riboside Chloride and CoQ10 support NAD+ biology and mitochondrial function — the foundation of how your cells make energy.*
Aminopeptide blend with L-Arginine, Glycine, and L-Glutamine, alongside a full vitamin and mineral panel — daily nutritional support for focus and mental performance.*
Resveratrol, Extramel® SOD, EGCG, and N-Acetyl L-Cysteine — research-backed antioxidants that support recovery from daily oxidative stress.*
A clinically formulated stack supporting two pathways at once — cellular energy through NAD+ biology, plus antioxidant defense for skin, hair, and connective tissue.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Recommended By
Fitness and nutrition unite for a vibrant, healthy lifestyle. That's why I take VitalFactors as my favorite natural energizer.
I take VitalFactors and give it to my patients. The only 'complaint' is that it makes our hair grow so fast, we need to visit the salon more.
VitalFactors is my fountain of youth — I have been taking it for over 20 years.
Customer Reviews
From 32 customer reviews
Popular topics
"I have been taking VitalFactors and other MDR vitamins for over 20 years. When you think I topped the charts before Elvis and I am still active and strong at 90, you can see why I call VitalFactors my 'Fountain of Youth.'"
"I take VitalFactors and give it to my patients. The only 'complaint' is that it makes our hair grow so fast, we need to visit the salon more."
"I was dragging thru the day and even felt like nodding off while driving. That was it. I tried Vital Factors because my friend said it gave her back her natural youthful energy. Within the first two days of me taking the drink, I was no longer getting tired. I felt more alert and had more focus to get more done. I also found I slept better. So grateful I found you. I will tell all my friends that aging doesn’t have to slow us down. Try MDR Vital Factors!"
"They work well, but I prefer the original formula. The original had a purple color, packed more of an energy kick, and tasted better. The original formula was a 5 - star product."
"Been taking VitalFactors for two months. Love the taste so much that it has become my favorite drink. Hate that I’m supposed to skip 2 days a week but I follow the regimen and am feeling amazing."
Customer reviews shown above are sourced from verified mdr.com purchases. Individual results vary — your purchase does not guarantee the same outcome.
FAQ
Individual results vary. Many customers report feeling a difference in energy and focus within the first few weeks of consistent use on the 5-on / 2-off rhythm. Because VitalFactors works through nutritional support rather than a stimulant effect, most benefits build gradually with regular use.*
Important information
Do not take this product if you have kidney, liver, or gastrointestinal disease, or cancer. Consult your physician first if you are on a sodium- or potassium-restricted diet.
VitalFactors contains soy isoflavones (sourced from soy). Free of gluten and artificial dyes. Not for individuals with a history of hypersensitivity to any ingredient — review the full Supplement Facts panel before use.
Not intended for individuals who are pregnant or nursing. Consult a health-care practitioner before using.
If you take prescription medications — particularly blood thinners, diabetes medications, or hormone therapies — consult your physician before starting VitalFactors.
Helpful tip: many customers paste their current medication list together with our Supplement Facts panel into ChatGPT to surface possible interactions worth discussing with their physician. It's not medical advice — just a useful starting point for that conversation.
Store in a cool, dry place away from direct sunlight or moisture. Do not store in the refrigerator. Keep out of reach of children or pets.
Contains no caffeine. Will not cause jitters or stimulant-type spikes.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.