VitalFactors box with effervescent tablet dissolving in glass
★★★★★4.8·Read reviews

VitalFactors®

Doctor-designed effervescent formulated to support daily energy, mental clarity, and healthy aging — for any healthy adult.*

Made in USAcGMP Compliant40 Years of ResearchNo Caffeine

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

The Approach

Two pathways. One daily formula.

NAD+ is a coenzyme involved in cellular energy production and DNA repair. Research suggests NAD+ levels decline with age (Imai et al., Nature Reviews 2014).*

A balanced amino-acid profile and clinical-grade vitamin and mineral panel provide the cofactors involved in normal cellular metabolism, recovery, and healthy aging.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Pathway 1 — Cellular Energy

Nicotinamide Riboside Chloride, Niacinamide, and CoQ10 are nutrients involved in NAD+biology and mitochondrial function.*

Pathway 2 — Healthy Aging

A clinically formulated blend of amino acids — L-Arginine, Glycine, L-Glutamine, and L-Ornithine — alongside antioxidants supports daily nutrition for healthy aging.*

How it works

Daily nutrition designed for the way the body actually works.

VitalFactors is a daily formula that combines NAD+-related cofactors, antioxidants, amino acids, and a full vitamin and mineral panel into two effervescent tablets — built to give any healthy adult a complete nutritional foundation in a single glass of water.*

  • Supports cellular energy and NAD⁺ biology*
  • Provides amino acids and cofactors involved in recovery*
  • Supports sleep quality and next-day vitality*
  • Supports mental clarity and focus*
  • Antioxidant defense against oxidative stress*
  • Supports healthy aging of skin, hair, and connective tissue*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  1. 1

    Take daily

    Drop two effervescent tablets in 8–12 oz of water each morning.

  2. 2

    Body absorbs

    The effervescent format dissolves the actives in water before you drink — designed for efficient absorption.

  3. 3

    Daily nutrition

    A complete vitamin, mineral, amino-acid, and antioxidant blend — daily nutritional support for any healthy adult.*

Compare

VitalFactors vs. typical NAD⁺ supplements.

FeatureVitalFactorsTypical NAD⁺ supplement
NAD⁺ precursorNicotinamide Riboside Chloride (Super NAD+)Often NMN or none
Amino-acid blend (Arginine, Glycine, Glutamine, Ornithine)
Antioxidant defense (Resveratrol, SOD, OPCs)
Foundational vitamin & mineral panel
Doctor-formulated since 1984
Effervescent — absorbs in solution
Made in USA, cGMP-compliantvaries
Monthly cost (subscribe)$89/mo$60–$120/mo

Allergy warning

Contains soy isoflavones (sourced from soy). Free of gluten and artificial dyes. If you have a known allergy to any ingredient, review the full Supplement Facts panel before use.

Pregnancy & nursing

Not intended for use during pregnancy or while nursing. Consult your physician before use if pregnant, planning a pregnancy, or nursing.

Drug interactions

If you take prescription medications — particularly blood thinners, diabetes medications, or hormone therapies — consult your physician before starting any new supplement.

Storage

Store in a cool, dry place away from direct sunlight. Keep tube tightly closed. Keep out of reach of children.

Recommended By

Doctors, journalists, and athletes who take it themselves.

Fitness and nutrition unite for a vibrant, healthy lifestyle. That's why I take VitalFactors as my favorite natural energizer.
Chris Cuomo
Chris Cuomo
TV journalist · NewsNation primetime anchor
I take VitalFactors and give it to my patients. The only 'complaint' is that it makes our hair grow so fast, we need to visit the salon more.
Dr. Lisa Learn
Dr. Lisa Learn
Board Certified Plastic & Reconstructive Surgeon
VitalFactors is my fountain of youth — I have been taking it for over 20 years.
Pat Boone
Singer & film star, age 90 · 20+ year user
VitalFactors keeps my immune system super strong.
Frank McKinney
Extreme athlete & author · 12× Badwater 135 finisher
I noticed more energy and better sleep — and my hair grew thicker and longer.
January Howard
Aesthetics consultant

Customer Reviews

What customers say.

4.8/ 5
★★★★★

Average customer rating

Popular topics

EnergySleepRecoveryFocusHairSkinImmuneValue
★★★★★VerifiedVerified customer

My fountain of youth

"I have been taking VitalFactors and other MDR vitamins for over 20 years. When you think I topped the charts before Elvis and I am still active and strong at 90, you can see why I call VitalFactors my 'Fountain of Youth.'"

Pat Boone·Singer · Film star · Age 90
★★★★★VerifiedVerified customer

I give it to my patients

"I take VitalFactors and give it to my patients. The only 'complaint' is that it makes our hair grow so fast, we need to visit the salon more."

Dr. Lisa Learn·Board Certified Plastic & Reconstructive Surgeon
★★★★★VerifiedVerified customer

Keeps my immune system super strong

"VitalFactors keeps my immune system super strong. I have run the Badwater 135-mile Ultramarathon 12x in Death Valley in July."

Frank McKinney·Extreme Athlete · Author
★★★★★VerifiedVerified customer

Energy, sleep, and hair

"I started VitalFactors and I first noticed more energy and better sleep. In a month, I was amazed to see my hair grew thicker and longer."

January Howard·Aesthetics Consultant

All testimonials shared are real and verified as customers. Your purchase does not guarantee the same results — individual results vary.

FAQ

Frequently asked.

Individual results vary. Many customers report feeling a difference in daily energy and focus within the first few weeks of consistent daily use. Because VitalFactors works through nutritional support rather than a stimulant effect, most benefits build gradually with regular use.*