VitalFactors — Age-Defying Nutritional Complex
Chris Cuomo's VitalFactors pick
Chris Cuomo, photographed for the VitalFactors campaign.
Chris Cuomo
Host, CUOMO on NewsNation · VitalFactors customer
Fitness and nutrition unite for a vibrant, healthy lifestyle. That's why I take VitalFactors as my favorite natural energizer.
— Chris Cuomo
VitalFactors · Cuomo Edition

Chris Cuomo’s VitalFactors routine.

One fizzy drink for healthy aging, energy, and recovery support.

Doctor formulated since 1984 · 4.8 rated · 60-day guarantee

Best value · 3-month supply
3-Month Supply · ships every 90 days
Then $249 every 3 months · cancel anytime
Just $78/mo to start, then $83/mo
Lower than $89/mo monthly · save $72/yr + a free $65 cream
$249/3 mo
$234
first order
$15 Cuomo discount applied today · code CUOMO
View ingredients

As heard with Chris Cuomo

  • cGMP compliant
  • Doctor-formulated
  • 5 days on · 2 days off
  • 40 years of research

Endorsement

Why Chris Cuomo talks about VitalFactors.

An Emmy-winning journalist and lifelong fitness advocate, Chris has said he uses VitalFactors as part of his nutrition routine. Here's what's actually in the box — and why it fits.

  • Daily energy support

    A complete B-complex plus an amino-acid blend supports the cofactors involved in normal cellular energy — without caffeine or added sugar.

  • Healthy aging nutrition

    NAD precursor, resVida® resveratrol, Extramel® SOD, and vitamin D3 designed to support the way you feel as you age — formulated by MDR physicians.

  • Effervescent morning routine

    Two tablets in a glass of water before a meal. Five days on, two days off. A drink, not another capsule to remember.

Why people take it

Show up sharper, steadier, and more like yourself.

VitalFactors is the fizzy drink that supports clean energy, mental clarity, and the kind of consistency that compounds — week after week, year after year.

  • Steady Energy
  • Immune Support
  • Mental Clarity
  • Heart Support
  • Muscle Tone
  • Healthy Skin

How VitalFactors works

One fizzy drink. The nutrients of a handful of pills.

VitalFactors is a complete wellness formula — vitamins, minerals, amino acids, antioxidants, and plant compounds — pressed into a single effervescent tablet. Drop it in water, and the nutrients are in solution and ready to absorb in under two minutes.

A glass of fizzing VitalFactors next to the VitalFactors box on a kitchen counter
  1. 01

    Drop two tablets into water

    Each effervescent tablet dissolves completely — vitamins, amino acids, antioxidants, and plant compounds go straight into solution. No capsule shell, no swallowing eight pills before breakfast.

  2. 02

    Drink the fizzy glass on your on-days

    Tablets in solution absorb through the stomach lining within minutes, instead of waiting on digestion. It's how Europeans have taken micronutrients for decades — the way the body was designed to receive them.

  3. 03

    Five days on, two days off

    The 5-on / 2-off rhythm gives the body two recovery days each week, so it stays responsive to the actives instead of adapting around them. Most customers run Mon–Fri and skip the weekend.

42+
years of clinical formulation
20
servings per box
0
caffeine · 0 sugar · 0 gluten
60-day
money-back guarantee

Customer Reviews

What customers say.

4.8/ 5
★★★★★

Popular topics

EnergySleepRecoveryFocusHairSkinImmuneValue
★★★★★VerifiedVerified customer

My fountain of youth

I have been taking VitalFactors and other MDR vitamins for over 20 years. I topped the charts before Elvis, and I am still active and strong today — which is why I call VitalFactors my 'Fountain of Youth.'

Pat Boone·Singer · Film star · 20+ year user
★★★★★VerifiedVerified customer

I give it to my patients

I take VitalFactors and give it to my patients. The only 'complaint' is that it makes our hair grow so fast, we need to visit the salon more.

Dr. Lisa Learn·Board Certified Plastic & Reconstructive Surgeon
★★★★★VerifiedNovember 2025

I was dragging thru the day and even felt like nodding off while driving. That was it. I tried Vital Factors because my friend said it gave her back her natural youthful energy. Within the first two days of me taking the drink, I was no longer getting tired. I felt more alert and had more focus to get more done. I also found I slept better. So grateful I found you. I will tell all my friends that aging doesn’t have to slow us down. Try MDR Vital Factors!

Chris
★★★★★VerifiedJune 2024

Been taking VitalFactors for two months. Love the taste so much that it has become my favorite drink. Hate that I’m supposed to skip 2 days a week but I follow the regimen and am feeling amazing.

Kara K.
★★★★★VerifiedOctober 2023

I was getting tired and needing to nap in the afternoon. I was putting off projects because I did not have the energy to tackle them. Now just one month after taking Vital Factors, I am my old me again…or i should say the YOUNGER ME again. I have more energy, mental sharpness, and don’t get tired but I fall asleep better at night. I am back to bicycling and swimming and feel healthier. Thanks for making this formula.

Tim

FAQ

Frequently asked.

Individual results vary. Many customers report feeling a difference in energy and focus within the first few weeks of consistent use on the 5-on / 2-off rhythm. Because VitalFactors works through nutritional support rather than a stimulant effect, most benefits build gradually with regular use.