One fizzy drink that makes the difference.
A NAD⁺ and amino-peptide effervescent on a 5-days-on, 2-days-off rhythm — formulated by MDR doctors since 1984. Give it 90 days to feel the full effect, then keep going.
One fizzy drink that makes the difference.
A NAD⁺ and amino-peptide effervescent on a 5-days-on, 2-days-off rhythm — formulated by MDR doctors since 1984. Give it 90 days to feel the full effect, then keep going.
Choose your plan
Why people take it
VitalFactors is the daily glass that supports clean energy, mental clarity, and the kind of consistency that compounds — week after week, year after year.
Inside the formula
The hero ingredients in VitalFactors — built to support cellular energy, recovery, and healthy aging in a single morning glass.
Cellular energy
Nicotinamide Riboside Chloride (Super NAD+) — a clinically studied precursor that supports your cellular NAD⁺ levels.
Recovery & repair
L-Arginine, Glycine, L-Glutamine, L-Lysine, and L-Ornithine — a balanced amino-peptide stack traditionally used by athletes for recovery and lean muscle support.
Antioxidant defense
Extramel® SOD — a patented melon-derived enzyme that supports your body’s defense against oxidative stress.
Longevity polyphenol
resVida® — clinically studied red-grape polyphenol associated with healthy-aging pathways.
The Approach
NAD+ is a coenzyme involved in cellular energy production and DNA repair. Research suggests NAD+ levels decline with age (Imai et al., Nature Reviews 2014).
A balanced amino-acid profile and clinical-grade vitamin and mineral panel provide the cofactors involved in normal cellular metabolism, recovery, and healthy aging.
Nicotinamide Riboside Chloride, Niacinamide, and CoQ10 are nutrients involved in NAD+biology and mitochondrial function.
A clinically formulated blend of amino acids — L-Arginine, Glycine, L-Glutamine, L-Lysine, and L-Ornithine — alongside antioxidants supports daily nutrition for healthy aging.
How it works
VitalFactors is a 5-days-on, 2-days-off effervescent that combines NAD+-related cofactors, antioxidants, amino peptides, and a full vitamin and mineral panel into two tablets — built to give any healthy adult a complete nutritional foundation in a single glass of water. The two-day pause each week keeps your body responsive to the actives instead of adapting around them.
Drop two effervescent tablets in 8–12 oz of water in the morning. Stay on the 5-on / 2-off rhythm.
The effervescent format dissolves the actives in water before you drink — designed for efficient absorption.
An advanced vitamin, mineral, amino-peptide, and antioxidant blend supplies nutritional support for peak performance and vibrant health.
What you get
Nicotinamide Riboside Chloride and CoQ10 support NAD+ biology and mitochondrial function — the foundation of how your cells make energy.
Methylcobalamin Vitamin B12 (8,333% DV) and a complete B-complex (B1, B2, B6, Folic Acid, Biotin) — micronutrients involved in healthy brain function and oxygen delivery to cells.
resVida® Resveratrol, Extramel® SOD, EGCG, and CoQ10 — research-backed antioxidants that protect cells against oxidative aging.
A clinically formulated stack supporting multiple pathways at once — cellular energy through NAD+ biology, recovery support via a balanced amino-peptide complex, and antioxidant defense from resVida®, Extramel® SOD, grape seed proanthocyanidins, and Lycopene.
Recommended By
Fitness and nutrition unite for a vibrant, healthy lifestyle. That's why I take VitalFactors as my favorite natural energizer.
Emmy-winning journalist and lifelong fitness advocate, Chris announced on his Cuomo Mornings show on SiriusXM that he had joined the many Americans who take MDR VitalFactors as part of their routine.
I take VitalFactors and give it to my patients. The only 'complaint' is that it makes our hair grow so fast, we need to visit the salon more.
VitalFactors is my fountain of youth — I have been taking it for over 20 years.
In their own words
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Customer Reviews
Popular topics
I have been taking VitalFactors and other MDR vitamins for over 20 years. When you think I topped the charts before Elvis and I am still active and strong at 90, you can see why I call VitalFactors my 'Fountain of Youth.'
I take VitalFactors and give it to my patients. The only 'complaint' is that it makes our hair grow so fast, we need to visit the salon more.
I was dragging thru the day and even felt like nodding off while driving. That was it. I tried Vital Factors because my friend said it gave her back her natural youthful energy. Within the first two days of me taking the drink, I was no longer getting tired. I felt more alert and had more focus to get more done. I also found I slept better. So grateful I found you. I will tell all my friends that aging doesn’t have to slow us down. Try MDR Vital Factors!
Been taking VitalFactors for two months. Love the taste so much that it has become my favorite drink. Hate that I’m supposed to skip 2 days a week but I follow the regimen and am feeling amazing.
I was getting tired and needing to nap in the afternoon. I was putting off projects because I did not have the energy to tackle them. Now just one month after taking Vital Factors, I am my old me again…or i should say the YOUNGER ME again. I have more energy, mental sharpness, and don’t get tired but I fall asleep better at night. I am back to bicycling and swimming and feel healthier. Thanks for making this formula.
The Research
VitalFactors is formulated from ingredients with a long publication history in peer-reviewed nutrition science. Tap an ingredient to see the studies.
Citations reflect the broader scientific literature for these ingredients and are provided for reference. They are not specific claims about VitalFactors or any individual outcome.
FAQ
Individual results vary. Many customers report feeling a difference in energy and focus within the first few weeks of consistent use on the 5-on / 2-off rhythm. Because VitalFactors works through nutritional support rather than a stimulant effect, most benefits build gradually with regular use.
Caution: Do not take this product if you have kidney, liver, or gastrointestinal disease, or cancer. Consult your physician first if you are on a sodium- or potassium-restricted diet.
Allergy: Contains soy isoflavones. Free of gluten and artificial dyes. Review the full Supplement Facts panel before use.
Pregnancy & nursing: Not intended for pregnant or nursing individuals. Consult a health-care practitioner before using.
Drug interactions: If you take prescription medications, especially blood thinners, diabetes medications, or hormone therapies, ask your physician or pharmacist before using VitalFactors.
Storage: Cool, dry place, away from direct sunlight or moisture. Do not refrigerate. Keep out of reach of children or pets.
Caffeine: Contains none.