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Caffeine-free cellular nutrition

Feel switched on.Without the spike.

A refreshing five-day ritual with 300 mg NMN, resveratrol, EGCG and S.O.D. No caffeine. No sugar. Nothing to swallow.

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VitalFactors box, two tablets and a glass of pink sparkling water
20 servings24 caloriesZero sugar
300 mg NMNin every serving
No caffeinesteady, stimulant-free support
5 days on, 2 offa simple weekly rhythm
90-day guaranteetime to decide if it fits

One box. One month. One easy ritual.

VitalFactors

4.9 from 35 customer reviews

A complete effervescent formula designed to support normal energy metabolism, antioxidant protection and healthy aging.

  • 300 mgNMN
  • 0 gsugar
  • 0 mgcaffeine
  • 20servings
Choose your option
Free shipping on subscriptions 90-day money-back guarantee
How to use

Drop two tablets into a glass of water, let them fully dissolve, and drink. Take VitalFactors five days on and two days off. One box contains 40 tablets, or 20 servings.

What is inside

300 mg NMN and 8 mg NADH, resVida® resveratrol, grape skin and seed extracts, EGCG from green tea and Extramel® S.O.D., plus vitamins, minerals, amino acids and CoQ10.

Shipping, returns & cancellation

Subscriptions and 3-month supplies ship free. Pause, skip or cancel a subscription online at any time. Every order is covered by a 90-day money-back guarantee.

Why it feels different

Support your energy. Skip the spike.

VitalFactors works with the body's normal energy and antioxidant systems. It is nutritional support, not a stimulant.

01

Energy without the stimulant cycle

NMN and B vitamins support the normal processes your body uses to convert nutrients into energy, without caffeine or sugar.

02

Whole-body support for mind and muscle

A broad formula of vitamins, minerals and amino acids helps support brain function, muscle function and everyday wellbeing.

03

Antioxidants for healthy aging

Resveratrol, EGCG, grape polyphenols and S.O.D. help support the body's antioxidant defenses against free radicals.

The five-minute habit

Drop. Fizz. Sip.

Two tablets. One glass. Five days a week.

  1. Two tablets into a glass of water.01

    Drop

    Two tablets into a glass of water.

  2. They dissolve completely and the water turns pink.02

    Fizz

    They dissolve completely and the water turns pink.

  3. Drink it five days a week, then take the weekend off.03

    Sip

    Drink it five days a week, then take the weekend off.

Formula transparency

Every active. Every amount.

We publish the complete formula, including every ingredient in the blend. No guessing and no hidden amounts.

  • Super NAD+

    300 mg NMN + 8 mg NADH

    NMN is a precursor your cells use to make NAD+, a coenzyme involved in normal energy metabolism.

  • Resveratrol

    resVida® + grape skin and seed

    Red grape polyphenols that help support antioxidant protection.

  • EGCG

    40 mg from green tea

    The best-known green tea catechin, a plant antioxidant.

  • S.O.D.

    Extramel® melon extract

    Superoxide dismutase from cantaloupe, an antioxidant enzyme.

Also in every serving: vitamins A, C, D3, E and a full B complex, calcium, magnesium, selenium and potassium, plus L-glutamine, L-arginine, L-lysine, glycine and CoQ10.

Three VitalFactors boxes packed for delivery

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Make consistency the easy part.

Your next box arrives every 30 days, right when you need it. No commitment and no call required to make changes.

  • $20 less than a single box
  • Free shipping on every delivery
  • Pause, skip or cancel online
  • 90-day money-back guarantee

Real routines. Real people.

They keep coming back to it.

4.935 customer reviews
Customer testimonial
Dr. Lisa Learn on VitalFactors
Customer testimonial
  • My favorite drink

    Been taking VitalFactors for two months. Love the taste so much that it has become my favorite drink. Hate that I’m supposed to skip 2 days a week but I follow the regimen and am feeling amazing.
    Kara K.June 2024 Customer review
  • I feel my best

    At age 76, I feel my absolute best when I take Vital Factors. It provides me the energy I need and the mental alertness to accomplish my goals on a daily basis. Also helps me accomplish my exercise goals.
    Judith H.December 2022 Customer review
  • My wife takes it too

    I have been taking VitalFactors for several years now and I can say I definitely see and feel the difference! I follow the recommended usage of five days on/two days off and it is working great for me. I now have my wife on this product and highly recommend it to anyone who wants to feel (and look) their best.
    John R.April 2022 Customer review
  • Twenty years and counting

    I've been taking/drinking Vital Factors for at least 20 years and never want to stop. The benefits are amazing! Thank you for making such a great vitamin drink.
    Lynn W.July 2022 Customer review
  • More energy and stamina

    I tried out the Vital Factors to see if I could tell any difference in how I felt. I take several supplements already. After a week I could tell that I had more energy and stamina than I had been having which is one of the reasons I wanted to try it. I am now on auto-ship and looking to see if the things it says it will do actually do. But just being able to have the needed energy will keep me taking it.
    Kathleen H.July 2022 Customer review
  • Easy to use

    Product easy to use, tablet dissolves easier now, and gives me more energy and focus just after a few days of starting it!
    Happy G.May 2022 Customer review
Pat Boone
VitalFactors has been part of my routine for over 20 years. I wouldn't skip a week.

Pat BooneSinger and film star, 20+ year customer

Dr. Lisa Learn
I take VitalFactors and recommend it to my patients: an easy part of a healthy routine.

Dr. Lisa LearnBoard Certified Plastic and Reconstructive Surgeon

Chris Cuomo
Fitness and nutrition go hand in hand. That's why I take VitalFactors as my favorite natural energizer.

Chris CuomoTV journalist, NewsNation

Pat Boone, Dr. Lisa Learn and Chris Cuomo are compensated endorsers.

Good to know

Questions, answered.

Need a real person? Call 1-800-637-8227.

How do I take VitalFactors?

Drop two tablets into a glass of water, let them dissolve, and drink. Take it five days on and two days off. Most people take it Monday to Friday and skip the weekend.

Why five days on and two days off?

VitalFactors has been designed around a weekly rhythm from the start. The cycle is what matters, not the exact days, and missing a day inside the week is fine.

How soon will I notice a difference?

Everyone is different. Many customers tell us they notice a difference within the first few weeks of taking it consistently. It is nutritional support, not a stimulant, so give it time.

Does it have caffeine or sugar?

No caffeine and no sugar. It is sweetened with monk fruit and stevia and has 24 calories per serving.

Can I cancel my subscription?

Yes. Pause, skip or cancel anytime from your MDR account. No phone call and no fees.

What if it isn't for me?

Every order is covered by our 90-day money-back guarantee. Call 1-800-637-8227 and we'll sort it out.

Does it contain allergens?

It contains soy. It does not contain dairy, gluten, yeast, eggs, fish, shellfish, tree nuts or peanuts.

Can I take it with my medications?

If you take prescription medication, especially blood thinners, diabetes medication or hormone therapy, ask your doctor or pharmacist before starting VitalFactors.

Who makes VitalFactors?

MDR, an American nutrition company that has been making supplements since 1984.

Your next good habit

Two tablets away from your first glass.

Start with free shipping and 90 days to decide.

Warnings and precautions

Caution: Do not take this product if you have kidney, liver or gastrointestinal disease, or cancer. Consult your physician first if you are on a sodium- or potassium-restricted diet.

Allergy: Contains soy. Review the full Supplement Facts panel before use.

Pregnancy and nursing: Not intended for pregnant or nursing individuals. Consult a health care practitioner before using.

Medications: If you take prescription medication, especially blood thinners, diabetes medication or hormone therapy, ask your physician or pharmacist before using VitalFactors.

Storage: Keep in a cool, dry place away from direct sunlight and moisture. Do not refrigerate. Keep out of reach of children and pets.