Daily nutrition for healthy aging
VitalFactors combines NAD support, amino acids, antioxidants, B vitamins, and vitamin D3 in a simple daily drink — designed to support vitality, mental clarity, recovery, and healthy aging.
What it supports
NAD precursors, CoQ10, and a complete B-complex provide the cofactors involved in how your cells make energy — the foundation of staying active.
Methylcobalamin B12 (8,333% DV), vitamin D3, and an amino-acid blend support healthy brain function and oxygen delivery to cells.
Resveratrol, Extramel® SOD, EGCG, vitamin C, and lycopene support antioxidant defense against the oxidative stress that accumulates over time.
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Most people start with one box to see how they feel. Subscribe later if you want to keep going — never the other way around.
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Made by Medical Doctors' Research
MDR — Medical Doctors' Research — has been formulating physician-grade supplements since 1984. VitalFactors is the formula MDR doctors built for adults who want to stay sharp, active, and consistent as they age. Used by board-certified surgeons, journalists, and 90-year-old film stars who still tour.
"I take VitalFactors and give it to my patients."
How it works
Two effervescent tablets, one glass of water, before breakfast. Five days on, two days off.
Stir, let them dissolve, drink. The effervescent format puts the actives into solution your stomach can absorb directly.
Take your two tablets in the morning Monday through Friday, then take a two-day break. The rhythm keeps the body responsive.
Most customers report feeling steadier energy and clearer focus inside the first month of consistent use.
Why this is different
A standard multivitamin covers basic vitamin deficiencies. VitalFactors adds the things that actually matter for healthy aging — NAD support, amino acids for recovery, and well-studied antioxidants — at meaningful doses.
| Feature | VitalFactors | Typical multivitamin |
|---|---|---|
| Complete vitamin & mineral panel | ||
| NAD⁺ precursor (Nicotinamide Riboside Chloride) | ||
| Amino-acid blend for recovery | ||
| Branded antioxidants (resVida® Resveratrol, Extramel® SOD) | ||
| B12 dosage | 8,333% DV (methylcobalamin) | Usually 100–500% DV |
| Effervescent — absorbs in solution | ||
| Doctor-formulated since 1984 | Varies |
Inside the formula
Plain-language descriptions of the non-obvious actives — the ingredients you don't typically find in a daily vitamin. Full quantities are on the Supplement Facts panel below.
A clinically studied NAD⁺ precursor — supports cellular NAD⁺ levels involved in how cells make energy.
Branded red-grape polyphenol associated with healthy-aging research pathways.
Patented melon-derived superoxide dismutase enzyme — supports antioxidant defense against oxidative stress.
Coenzyme central to mitochondrial energy production — supports cellular energy.
A balanced amino-acid stack traditionally used by athletes for recovery and lean muscle support.
Supports healthy brain function and red blood cells, which carry oxygen to cells.
A complete B-vitamin panel involved in normal cellular metabolism and energy production.
Supports bone, mood, and immune health — the form your body uses most efficiently.
Antioxidant vitamin that supports immune defense and collagen formation.
Polyphenol antioxidant that supports oxidative balance.
Antioxidant from tomatoes that supports a healthy cardiovascular system and youthful skin.
Concentrated polyphenols layered on top of resVida® for full-spectrum antioxidant support.
Brown seaweed extract rich in marine polysaccharides — studied for immune support.
Patented botanical complex (Nelumbo Nucifera) traditionally associated with DNA repair pathways.
Supplement Facts
Serving size 2 tablets · 20 servings per container. Tap below to see the complete panel with every ingredient, amount, and % Daily Value.
Customer reviews
Real reviews from verified MDR customers — pulled from the live store, prioritizing feedback about staying active, recovery, and long-term consistency.
I was dragging thru the day and even felt like nodding off while driving. That was it. I tried Vital Factors because my friend said it gave her back her natural youthful energy. Within the first two days of me taking the drink, I was no longer getting tired. I felt more alert and had more focus to get more done. I also found I slept better. So grateful I found you. I will tell all my friends that aging doesn’t have to slow us down. Try MDR Vital Factors!
I have been taking VitalFactors for several years now and I can say I definitely see and feel the difference! I follow the recommended usage of five days on/two days off and it is working great for me. I now have my wife on this product and highly recommend it to anyone who wants to feel (and look) their best.
I’ve been using this product for years and have never been disappointed. The product does what it says,, gives energy and vitality.
I was getting tired and needing to nap in the afternoon. I was putting off projects because I did not have the energy to tackle them. Now just one month after taking Vital Factors, I am my old me again…or i should say the YOUNGER ME again. I have more energy, mental sharpness, and don’t get tired but I fall asleep better at night. I am back to bicycling and swimming and feel healthier. Thanks for making this formula.
Carolyn Ryznar Lygo - September 22, 2023 FANTASTIC! "PLOP, PLOP, FIZZ, FIZZ" ...OH WHAT A DELIGHT VITAL FACTORS IS! I am a 78 year old widow on Home Hospice Care for Pulmonary decline and much weakness for the last 3 years. The first time I drank it, a significant boost of energy and even strength entered my body - I was surprised!!! BUT SHOULD NOT HAVE BEEN. At this time in my life this life enhancing elixir has made a significant improvement in my body, emotions and will to keep going. Thank You Pat Riley for your dedicated research and quality product line that I have been using for years.…
FANTASTIC! " PLOP,PLOP, FIZZ,FIZZ."...OH WHAT A DELIGHT VITAL FACTORS IS! I am a 78 widow on Home Hospice with serious pulmonary disease resulting in spells and general declining weakness for the last 3 years. First time I took this elixir, my body responded like a miracle! I got my energy back & now with continued use truly enjoy a raised quality of life. Vital Factor's is just one of the miracle formulas Pat Riley has formulated. 5 STARS!! Makes my life far more fulfilling in these last days.
Safety
VitalFactors is a daily nutritional formula made of vitamins, minerals, amino acids, and well-studied botanicals — not a drug. For most healthy adults it's a straightforward addition to a daily routine.
If you take prescription medications — especially blood thinners, diabetes medications, or hormone therapies — ask your physician or pharmacist before use. If you have kidney, liver, or gastrointestinal disease, or if you're pregnant or nursing, consult your physician first.
Contains soy isoflavones (a plant-based polyphenol). Free of gluten, dairy, eggs, fish, shellfish, tree nuts, peanuts, and animal ingredients.
Risk-free to try
Cold-traffic landing pages on the internet are notorious for sneaky checkouts. We don't do that. Here's exactly what you get.
Every order ships free in the US, usually within 24 hours.
Don't feel a difference? Send it back within 90 days for a refund of the product cost.
If you choose a subscription, cancel or pause from your account in two clicks. No phone call, no fees.
FAQ
VitalFactors is formulated as daily nutrition for healthy adults of any age, including older adults. Many of our long-term customers are in their 70s, 80s, and 90s. If you have a chronic condition or take prescription medications, run the Supplement Facts panel by your physician first — that's just sensible practice with any supplement at any age.
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