NAD support · cellular health
VitalFactors delivers NAD-supporting nutrition with amino acids, antioxidants, B vitamins, vitamin D3, and resveratrol — in an effervescent formula built for daily cellular health support.
What is NAD support?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme your cells use for energy production and DNA repair. It sits at the center of how your body actually makes and spends energy.
Research suggests NAD+ levels decline with age — by your 40s and beyond, levels can be a fraction of what they were earlier in life. (Imai & Guarente, Trends in Cell Biology, 2014)
"NAD support" means giving the body the precursor nutrients it uses to make NAD+. VitalFactors uses Nicotinamide Riboside Chloride — a clinically studied NAD+ precursor — alongside other cofactors involved in cellular energy biology.
VitalFactors is a daily nutritional formula. It's not a drug and not a treatment for any condition. It's the same kind of daily nutrition routine as taking a vitamin — with ingredients chosen for cellular health support.
What the formula supports
Nicotinamide Riboside Chloride is a precursor your cells use to make NAD⁺. CoQ10 and Niacinamide are layered alongside as cofactors involved in mitochondrial energy biology.
resVida® Resveratrol, Extramel® SOD, EGCG green-tea polyphenols, and grape seed proanthocyanidins support antioxidant defense against oxidative stress.
L-Arginine, Glycine, L-Glutamine, L-Lysine, and L-Ornithine — a balanced amino-acid stack used by athletes for recovery and lean muscle support.
Choose how you want to start
Most people start with one box to see how they feel. Subscribe later if you want to keep going — never the other way around.
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Why this is different
Most NAD products are a single capsule with one precursor and a markup. VitalFactors layers the NAD precursor inside a complete daily nutrition formula — at a per-day cost that's usually lower than capsule-only alternatives.
| Feature | VitalFactors | Typical NAD capsule |
|---|---|---|
| NAD⁺ precursor | Nicotinamide Riboside Chloride | NMN or NR alone |
| Resveratrol (resVida®) | ||
| SOD antioxidant (Extramel®) | ||
| Amino-acid blend | ||
| Complete vitamin & mineral panel | ||
| Format | Effervescent in water | Capsule |
| Daily cost (one box) | ~$3.30/day | Often $4–8/day |
What's in the glass
Branded, well-studied ingredients you can verify on the bottle. Full quantities are on the Supplement Facts panel below — no hidden proprietary blends.
A clinically studied NAD⁺ precursor — supports cellular NAD⁺ levels involved in how cells make energy.
Branded red-grape polyphenol associated with healthy-aging research pathways.
Patented melon-derived superoxide dismutase enzyme — supports antioxidant defense against oxidative stress.
Coenzyme central to mitochondrial energy production — supports cellular energy.
A balanced amino-acid stack traditionally used by athletes for recovery and lean muscle support.
Polyphenol antioxidant that supports oxidative balance.
Concentrated polyphenols layered on top of resVida® for full-spectrum antioxidant support.
Patented botanical complex (Nelumbo Nucifera) traditionally associated with DNA repair pathways.
Supplement Facts
Serving size 2 tablets · 20 servings per container. Tap below to see the complete panel with every ingredient, amount, and % Daily Value.
How it works
Two effervescent tablets in water in the morning. Five days on, two days off. That's the entire protocol.
The effervescent format dissolves the actives — including the NAD precursor — into solution your stomach absorbs directly, rather than waiting on a capsule shell to break down.
Take it Monday through Friday, then take a two-day break on weekends. The rhythm is what MDR doctors found keeps the body responsive to the actives.
For best results, take VitalFactors at least 30 minutes before eating, and follow with light exercise — many customers do.
Customer reviews
Real reviews from verified MDR customers — pulled from the live store, prioritizing feedback about energy, recovery, and clarity.
I was dragging thru the day and even felt like nodding off while driving. That was it. I tried Vital Factors because my friend said it gave her back her natural youthful energy. Within the first two days of me taking the drink, I was no longer getting tired. I felt more alert and had more focus to get more done. I also found I slept better. So grateful I found you. I will tell all my friends that aging doesn’t have to slow us down. Try MDR Vital Factors!
I was getting tired and needing to nap in the afternoon. I was putting off projects because I did not have the energy to tackle them. Now just one month after taking Vital Factors, I am my old me again…or i should say the YOUNGER ME again. I have more energy, mental sharpness, and don’t get tired but I fall asleep better at night. I am back to bicycling and swimming and feel healthier. Thanks for making this formula.
Carolyn Ryznar Lygo - September 22, 2023 FANTASTIC! "PLOP, PLOP, FIZZ, FIZZ" ...OH WHAT A DELIGHT VITAL FACTORS IS! I am a 78 year old widow on Home Hospice Care for Pulmonary decline and much weakness for the last 3 years. The first time I drank it, a significant boost of energy and even strength entered my body - I was surprised!!! BUT SHOULD NOT HAVE BEEN. At this time in my life this life enhancing elixir has made a significant improvement in my body, emotions and will to keep going. Thank You Pat Riley for your dedicated research and quality product line that I have been using for years.…
FANTASTIC! " PLOP,PLOP, FIZZ,FIZZ."...OH WHAT A DELIGHT VITAL FACTORS IS! I am a 78 widow on Home Hospice with serious pulmonary disease resulting in spells and general declining weakness for the last 3 years. First time I took this elixir, my body responded like a miracle! I got my energy back & now with continued use truly enjoy a raised quality of life. Vital Factor's is just one of the miracle formulas Pat Riley has formulated. 5 STARS!! Makes my life far more fulfilling in these last days.
At age 76, I feel my absolute best when I take Vital Factors. It provides me the energy I need and the mental alertness to accomplish my goals on a daily basis. Also helps me accomplish my exercise goals.
Vital factors is a supplement that give me strength to move around and do more it taste good and make me feel full of energy. I take it on a empty stomach it’s has vitamins that my body needs thank to vital factors I can feel younger and better.
Made by Medical Doctors' Research
VitalFactors isn't a venture-backed pivot into longevity — it's a forty-year-old physician-led nutrition company adding NAD support to a formula it's been refining since the mid-1980s. Every batch is manufactured in cGMP-compliant US facilities.
"I take VitalFactors and give it to my patients."
Safety
VitalFactors is a daily nutritional formula made of vitamins, minerals, amino acids, and well-studied botanicals — not a drug. For most healthy adults it's a straightforward addition to a daily routine.
If you take prescription medications — especially blood thinners, diabetes medications, or hormone therapies — ask your physician or pharmacist before use. If you have kidney, liver, or gastrointestinal disease, or if you're pregnant or nursing, consult your physician first.
Contains soy isoflavones (a plant-based polyphenol). Free of gluten, dairy, eggs, fish, shellfish, tree nuts, peanuts, and animal ingredients.
Risk-free to try
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Every order ships free in the US, usually within 24 hours.
Don't feel a difference? Send it back within 90 days for a refund of the product cost.
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FAQ
NAD⁺ is a coenzyme your cells use to make energy and repair DNA. 'NAD support' means giving the body the precursor nutrients it uses to make NAD⁺. VitalFactors uses Nicotinamide Riboside Chloride — a clinically studied precursor — as its NAD-support ingredient.
Ready when you are
One box is a month of daily NAD-supporting nutrition. Start there.
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